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5 Plasma Caster Coin Flip Exile Plasma Caster is the best Equipment found with Science

Also, creatures that grant boons on death like Thragtusk or Wurmcoil Engine could find a home in a self-wipe deck, although the Wurm might be outclassed then by something more traditional like Austere Command , Settle the Wreckage , Kindred Dominance , or Phyrexian Rebirth .

It is a sorcery that costs 2 black and 7 generic that reads: Destroy all creatures you dont control

If you win, prevent all damage that would be dealt this turn by a source of your choice

I'll need a token in play for it to work, but I'm optimistic that I'll usually be able to make a Squirrel or something to target with it